Wearable drug delivery device, insertion mechanism therefor, and method of operating a wearable drug delivery device

• Main Authors: DECKER, ROBERT, BOYAVAL, MARGAUX FRANCES, BENTE, PAUL F. IV, BOKELMAN, KEVIN L, O'CONNOR, SEAN M, DESTEFANO, MARK A, AGARD, RYAN M, SHETTY, GAUTAM N, LOVE, JOHN C, BEAVER, SCOTT, CICCARELLI, NICHOLAS J, GIBSON, SCOTT R, HANSON, IAN B, RAMASWAMY, RAJAN, CODD, DANIEL S, DAVENPORT, DANIEL, MOBERG, SHELDON B, TAHA, BASEL HASAN, CLEMENTE, MATTHEW J
• Format: Patent
• Language: Chinese; English
• Published: 21.03.2023
• Subjects: BABY COMFORTERS; CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICALPURPOSES; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR; DEVICES FOR RECEIVING SPITTLE; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGINGPHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL ORADMINISTERING FORMS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE

Disclosed herein is a wearable drug delivery device including a container filled at least partially with a drug including at least one of a PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) specific antibody, a granulocyte colony-stimulating factor (G-CSF), a sclerostin antibody, or a calcitonin gene-related peptide (CGRP) antibody. The wearable drug delivery device may include a needle and an insertion mechanism configured to insert the needle into a patient. A fluid pathway connector may define a sterile fluid flowpath between the container and the insertion mechanism. Optionally, a cannula initially disposed about the needle may be included. The cannula may be retained in the patient at an injection site created by the needle after the needle is withdrawn from the patient. Methods of assembly and operation are also provided.