Suspension for oral administration comprising amorphous tolvaptan

• Main Authors: SUZUKI, KAI, NAKAMURA, ATSUYA, AKAGI, AKITSUNA, NISHIBAYASHI, TORU
• Format: Patent
• Language: Chinese; English
• Published: 01.06.2019
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

This invention provides a suspension for oral administration comprising particles containing amorphous tolvaptan that can inhibit or delay crystallization of amorphous tolvaptan over time in the suspension, and stably maintain high solubility of tolvaptan and excellent absorbability of tolvaptan fro...