Pyrazolone derivatives as nitroxyl donors

The disclosed subject matter provides pyrazolone derivative compounds, pharmaceutical compositions comprising such compounds, kits comprising such compounds, and methods of using such compounds or pharmaceutical compositions. In particular, the disclosed subject matter provides methods of using such...

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Bibliographic Details
Main Authors TOSCANO, JOHN P, BROOKFIELD, FREDERICK ARTHUR, FROST, LISA MARIE, NORTH, CARL LESLIE, KALISH, VINCENT JACOB, GUTHRIE, DARYL A, COURTNEY, STEPHEN MARTIN
Format Patent
LanguageChinese
English
Published 21.05.2019
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The disclosed subject matter provides pyrazolone derivative compounds, pharmaceutical compositions comprising such compounds, kits comprising such compounds, and methods of using such compounds or pharmaceutical compositions. In particular, the disclosed subject matter provides methods of using such compounds or pharmaceutical compositions for treating heart failure.
Bibliography:Application Number: TW20154117089