Compounds, compositions, and methods of using thereof

• Main Authors: HIRTH, BRAD, KOTHE, MICHAEL, LIU, JINYU, RACKELMANN, NILS, GENEVOIS-BORELLA, ARIELLE, GLOMBIK, HEINER, BERNARDELLI, PATRICK, RUVINSKY, ANATOLY, PODESCHWA, MICHAEL, THURAIRATNAM, SUKANTHINI, RUF, SVEN, BORCHERDING, DAVID, DEVILLERS, INGRID, GUESSREGEN, STEFAN, MACOR, JOHN, GOOD, ANDREW, LI, YI, GAO, ZHONGLI, NICOLAI, ERIC, SLOWINSKI, FRANCK, THOMPSON, FABIENNE, TOPALOV, GEORGE, SCHWINK, LOTHAR, MUNSON, MARK, CAUSSANEL, FRANCK, LIAO, JUNKAI, VAZ, ROY, HURLBUT, GREG
• Format: Patent
• Language: Chinese; English
• Published: 01.07.2024
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present disclosure includes, among other things, CFTR modulators, pharmaceutical compositions, and methods of making and using the same.