Compounds and compositions for the treatment of coronaviral related diseases

Provided herein are compounds and compositions for treating, managing or preventing coronaviral related diseases. In particular, provided herein are compounds which are inhibitors of SARS-CoV-2 main protease (Mpro), pharmaceutical compositions comprising such compounds, method for synthesizing such...

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Main Authors PAPILLON, JULIEN, ZHANG, TENG, HESSE, MATTHEW JAMES, GUO, FENG-FENG, HORNAK, VIKTOR, QU, YANG, JOSEPH, SAJAN, MIAO, YA-NAN, MOSER, HEINZ ERNST, LIN, HAI-YAO, BAO, DENG-HUI, YUAN, JUN, KIRRANE, THOMAS MARTIN JR, LIU, BO, SHI, LEI
Format Patent
LanguageChinese
English
Published 01.06.2023
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Abstract Provided herein are compounds and compositions for treating, managing or preventing coronaviral related diseases. In particular, provided herein are compounds which are inhibitors of SARS-CoV-2 main protease (Mpro), pharmaceutical compositions comprising such compounds, method for synthesizing such compounds and methods of using such compounds and compositions for the treatment, management or prevention of coronaviral related diseases.
AbstractList Provided herein are compounds and compositions for treating, managing or preventing coronaviral related diseases. In particular, provided herein are compounds which are inhibitors of SARS-CoV-2 main protease (Mpro), pharmaceutical compositions comprising such compounds, method for synthesizing such compounds and methods of using such compounds and compositions for the treatment, management or prevention of coronaviral related diseases.
Author LIN, HAI-YAO
SHI, LEI
QU, YANG
ZHANG, TENG
KIRRANE, THOMAS MARTIN JR
MOSER, HEINZ ERNST
BAO, DENG-HUI
LIU, BO
MIAO, YA-NAN
GUO, FENG-FENG
HORNAK, VIKTOR
HESSE, MATTHEW JAMES
JOSEPH, SAJAN
PAPILLON, JULIEN
YUAN, JUN
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– fullname: MOSER, HEINZ ERNST
– fullname: LIN, HAI-YAO
– fullname: BAO, DENG-HUI
– fullname: YUAN, JUN
– fullname: KIRRANE, THOMAS MARTIN JR
– fullname: LIU, BO
– fullname: SHI, LEI
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Snippet Provided herein are compounds and compositions for treating, managing or preventing coronaviral related diseases. In particular, provided herein are compounds...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title Compounds and compositions for the treatment of coronaviral related diseases
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