Multiparameter materials, methods and systems for bioreactor glycated species manufacture

Methods for determining glycation on a molecule and/or a glycan structure on a glycosylated molecule through the use of a combination of spectroscopic analysis and chemometric modeling are described. In addition, methods and systems for producing a molecule with a desired level of glycation, includi...

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Main Authors MADDEN, FIONA, MASLANKA, FRANCIS C, O''MAHONY-HARTNETT, CAITLIN, TROUT, DANIEL A, RAFFERTY, CARL, RANA, PUSHPRAJ, GRATSIA, EMMANOUELA, BALSS, KARIN M, MO, JINGJIE, HAYES, RONAN, CLARK, KEVIN, MCCARTHY, BARRY J, RODE, CHRISTOPHER W
Format Patent
LanguageChinese
English
Published 01.02.2023
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Summary:Methods for determining glycation on a molecule and/or a glycan structure on a glycosylated molecule through the use of a combination of spectroscopic analysis and chemometric modeling are described. In addition, methods and systems for producing a molecule with a desired level of glycation, including a non-glycated molecule, and/or a desired level of a glycan structure on a glycosylated molecule are described.
Bibliography:Application Number: TW202211110646