Replication stress pathway agent compositions and methods for treating cancer

Provided herein are methods of treating cancer in a subject, wherein the cancer is extrachromosomal DNA-positive (ecDNA-positive) or therapeutically resistant, the method comprising administering to the subject a therapeutically effective amount of a replication stress (RS) pathway agent alone or in...

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Main Authors HORNBY, ZACHARY, HASSIG, CHRISTIAN, MILUTINOVIC, SNEZANA, CELESTE, ANTHONY, HANSEN, RYAN, CHRISTIANSEN, JASON, TURNER, KRISTEN, CHOWDHRY, SUDHIR
Format Patent
LanguageChinese
English
Published 01.06.2022
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Summary:Provided herein are methods of treating cancer in a subject, wherein the cancer is extrachromosomal DNA-positive (ecDNA-positive) or therapeutically resistant, the method comprising administering to the subject a therapeutically effective amount of a replication stress (RS) pathway agent alone or in combination with a targeted therapeutic.
Bibliography:Application Number: TW202110129785