Oligonucleotide agonists targeting progranulin
The present invention relates to oligonucleotides which up-regulate or restore the expression of progranulin in cells, and their use in the treatment of neurological disorders, and disorders associated with progranulin haploinsufficiency.
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| Main Authors | , , , , , |
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| Format | Patent |
| Language | Chinese English |
| Published |
01.03.2022
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| Subjects | |
| Online Access | Get full text |
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| Abstract | The present invention relates to oligonucleotides which up-regulate or restore the expression of progranulin in cells, and their use in the treatment of neurological disorders, and disorders associated with progranulin haploinsufficiency. |
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| AbstractList | The present invention relates to oligonucleotides which up-regulate or restore the expression of progranulin in cells, and their use in the treatment of neurological disorders, and disorders associated with progranulin haploinsufficiency. |
| Author | LARSEN, DORTHE VANG RASMUSSEN, SOREN TEHLER, DISA JAGASIA, RAVI JOENSON, LARS WORM, JESPER |
| Author_xml | – fullname: JAGASIA, RAVI – fullname: WORM, JESPER – fullname: LARSEN, DORTHE VANG – fullname: RASMUSSEN, SOREN – fullname: TEHLER, DISA – fullname: JOENSON, LARS |
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| RelatedCompanies | F. HOFFMANN-LA ROCHE AG |
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| Snippet | The present invention relates to oligonucleotides which up-regulate or restore the expression of progranulin in cells, and their use in the treatment of... |
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| Title | Oligonucleotide agonists targeting progranulin |
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