Engineered transferrin receptor binding polypeptides

• Main Authors: DENNIS, MARK S, CHEN, XIAOCHENG, WELLS, ROBERT C, ZUCHERO, JOY YU, WATTS, RYAN J, KARIOLIS, MIHALIS, SILVERMAN, ADAM P, SRIVASTAVA, ANKITA
• Format: Patent
• Language: Chinese; English
• Published: 01.06.2019
• Subjects: CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

Provided herein are polypeptides that bind to a transferrin receptor, Fc dimers and fusion proteins comprising such polypeptides, and methods of using the polypeptides to target a composition to a transferrin receptor-expressing cell.