Engineered transferrin receptor binding polypeptides

Provided herein are polypeptides that bind to a transferrin receptor, Fc dimers and fusion proteins comprising such polypeptides, and methods of using the polypeptides to target a composition to a transferrin receptor-expressing cell.

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Main Authors DENNIS, MARK S, CHEN, XIAOCHENG, WELLS, ROBERT C, ZUCHERO, JOY YU, WATTS, RYAN J, KARIOLIS, MIHALIS, SILVERMAN, ADAM P, SRIVASTAVA, ANKITA
Format Patent
LanguageChinese
English
Published 01.06.2019
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Abstract Provided herein are polypeptides that bind to a transferrin receptor, Fc dimers and fusion proteins comprising such polypeptides, and methods of using the polypeptides to target a composition to a transferrin receptor-expressing cell.
AbstractList Provided herein are polypeptides that bind to a transferrin receptor, Fc dimers and fusion proteins comprising such polypeptides, and methods of using the polypeptides to target a composition to a transferrin receptor-expressing cell.
Author WELLS, ROBERT C
SILVERMAN, ADAM P
CHEN, XIAOCHENG
WATTS, RYAN J
SRIVASTAVA, ANKITA
DENNIS, MARK S
ZUCHERO, JOY YU
KARIOLIS, MIHALIS
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– fullname: WATTS, RYAN J
– fullname: KARIOLIS, MIHALIS
– fullname: SILVERMAN, ADAM P
– fullname: SRIVASTAVA, ANKITA
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Snippet Provided herein are polypeptides that bind to a transferrin receptor, Fc dimers and fusion proteins comprising such polypeptides, and methods of using the...
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SubjectTerms CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Title Engineered transferrin receptor binding polypeptides
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