Process to produce adipic acid and diesters thereof in a carbonylation process using palladium bidentate biphosphate ligands

• Main Authors: DE VRIES, JOHANNES GERAEDUS, VAN DE VONDERVOORT, ELISABETH WILHELMINA MARIA, JANSSEN, MICHELE CATHERINE CHRISTIANNE, SEREINIG, NATASCHA
• Format: Patent
• Language: Chinese; English
• Published: 16.12.2012
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY; CHEMISTRY; METALLURGY; ORGANIC CHEMISTRY; PERFORMING OPERATIONS; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL; THEIR RELEVANT APPARATUS; TRANSPORTING

The invention relates to a carbonylation process for the preparation of a compound of formula I XOOC-(CH2)4-COOY (I) wherein X and Y can independently represent H and/or alkyl, said carbonylation process comprising reacting: (a) a composition comprising at least one isomeric methyl pentenoate; (b) a source of Pd; (c) a bidentate di-phosphine of formula II, R1R2P - R3 - R - R4 - PR5R6 (II) wherein P represents a phosphorus atom; R1, R2, R5 and R6 can independently represent the same or different optionally substituted organic groups containing a tertiary carbon atom through which the group is linked to the phosphorus atom; R3 and R4 independently represent optionally substituted lower alkylene groups and R represents an optionally substituted aromatic group; (d) a source of anions derived from an acid with a pKa < 3; (e) carbon monoxide; and (f) an OH group comprising compound, under conditions wherein (I) is produced, characterized in that the least one isomeric methyl pentenoate comprises methyl 2-pentenoate