Novel piperazine salts as D3/D2 antagonists
The present invention relates to novel monohydrochloride, dihydrochloride, monohydrobromide, maleate and methanesulphonate salts of trans 4-{2-[4-(2,3-dichlorophenyl)-piperazine-1-yl]-ethyl}-N,N-dimethylcarbamoyl-cycloh exylamine and/or their hydrates and/or solvates. Moreover, the invention relates...
Saved in:
| Main Authors | , , , , |
|---|---|
| Format | Patent |
| Language | Chinese English |
| Published |
16.01.2010
|
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | The present invention relates to novel monohydrochloride, dihydrochloride, monohydrobromide, maleate and methanesulphonate salts of trans 4-{2-[4-(2,3-dichlorophenyl)-piperazine-1-yl]-ethyl}-N,N-dimethylcarbamoyl-cycloh exylamine and/or their hydrates and/or solvates. Moreover, the invention relates to the process for preparing the salts and their hydrates and/or solvates, to their use in the treatment and/or prevention of conditions which require modulation of dopamine receptor and to pharmaceutical compositions containing them. |
|---|---|
| AbstractList | The present invention relates to novel monohydrochloride, dihydrochloride, monohydrobromide, maleate and methanesulphonate salts of trans 4-{2-[4-(2,3-dichlorophenyl)-piperazine-1-yl]-ethyl}-N,N-dimethylcarbamoyl-cycloh exylamine and/or their hydrates and/or solvates. Moreover, the invention relates to the process for preparing the salts and their hydrates and/or solvates, to their use in the treatment and/or prevention of conditions which require modulation of dopamine receptor and to pharmaceutical compositions containing them. |
| Author | GREINER, ISTVAN DOMANY, GYORGY AGAINE CSONGOR, EVA SEBOK, FERENC CZIBULA, LASZLO |
| Author_xml | – fullname: AGAINE CSONGOR, EVA – fullname: GREINER, ISTVAN – fullname: SEBOK, FERENC – fullname: DOMANY, GYORGY – fullname: CZIBULA, LASZLO |
| BookMark | eNrjYmDJy89L5WTQ9ssvS81RKMgsSC1KrMrMS1UoTswpKVZILFZwMdZ3MVJIzCtJTM_PyywuKeZhYE1LzClO5YXS3AyKbq4hzh66qQX58anFBYnJqXmpJfEh4UYGhgYGRsZGxo7GxKgBAAd2Kns |
| ContentType | Patent |
| DBID | EVB |
| DatabaseName | esp@cenet |
| DatabaseTitleList | |
| Database_xml | – sequence: 1 dbid: EVB name: esp@cenet url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP sourceTypes: Open Access Repository |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine Chemistry Sciences |
| ExternalDocumentID | TW201002323A |
| GroupedDBID | EVB |
| ID | FETCH-epo_espacenet_TW201002323A3 |
| IEDL.DBID | EVB |
| IngestDate | Fri Jul 19 12:59:53 EDT 2024 |
| IsOpenAccess | true |
| IsPeerReviewed | false |
| IsScholarly | false |
| Language | Chinese English |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-epo_espacenet_TW201002323A3 |
| Notes | Application Number: TW200897125707 |
| OpenAccessLink | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20100116&DB=EPODOC&CC=TW&NR=201002323A |
| ParticipantIDs | epo_espacenet_TW201002323A |
| PublicationCentury | 2000 |
| PublicationDate | 20100116 |
| PublicationDateYYYYMMDD | 2010-01-16 |
| PublicationDate_xml | – month: 01 year: 2010 text: 20100116 day: 16 |
| PublicationDecade | 2010 |
| PublicationYear | 2010 |
| RelatedCompanies | RICHTER GEDEON NYRT |
| RelatedCompanies_xml | – name: RICHTER GEDEON NYRT |
| Score | 2.8649116 |
| Snippet | The present invention relates to novel monohydrochloride, dihydrochloride, monohydrobromide, maleate and methanesulphonate salts of trans... |
| SourceID | epo |
| SourceType | Open Access Repository |
| SubjectTerms | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| Title | Novel piperazine salts as D3/D2 antagonists |
| URI | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20100116&DB=EPODOC&locale=&CC=TW&NR=201002323A |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwY2BQSTMxtzCxNErRNTBKStU1STNK1rU0N07SNUq1SDQxS7UwSrUE7Ub29TPzCDXxijCNYGLIgu2FAZ8TWg4-HBGYo5KB-b0EXF4XIAaxXMBrK4v1kzKBQvn2biG2LmrQ3rEheF5BzcXJ1jXA38XfWc3Z2TYkXM0vCCIHbD0YOzIzsAKb0eag3OAa5gTalVKAXKW4CTKwBQBNyysRYmCqyhBm4HSG3bwmzMDhC53wBjKhea9YhEHbL78sNUehILMgtQh8JrRCcWJOSbFCYrGCi7G-i5ECMIwS0_NBJ-EWizIourmGOHvoAm2Nh3sxPiQc4UBjMQYWYNc_VYJBwTTNDNg8SrMwBoahiUFKYlKiiVFqSlKyZZJxWqpBcpokgxRuc6TwSUozcEHmwUHXRMswsJQUlabKAqvXkiQ5cLgAAJXrfoE |
| link.rule.ids | 230,309,783,888,25576,76876 |
| linkProvider | European Patent Office |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwY2BQSTMxtzCxNErRNTBKStU1STNK1rU0N07SNUq1SDQxS7UwSrUE7Ub29TPzCDXxijCNYGLIgu2FAZ8TWg4-HBGYo5KB-b0EXF4XIAaxXMBrK4v1kzKBQvn2biG2LmrQ3rEheF5BzcXJ1jXA38XfWc3Z2TYkXM0vCCIHbD0YOzIzsAKb2Oag3OAa5gTalVKAXKW4CTKwBQBNyysRYmCqyhBm4HSG3bwmzMDhC53wBjKhea9YhEHbL78sNUehILMgtQh8JrRCcWJOSbFCYrGCi7G-i5ECMIwS0_NBJ-EWizIourmGOHvoAm2Nh3sxPiQc4UBjMQYWYNc_VYJBwTTNDNg8SrMwBoahiUFKYlKiiVFqSlKyZZJxWqpBcpokgxRuc6TwScozcHqE-PrE-3j6eUszcEHmxEFXRsswsJQUlabKAqvakiQ5cBgBAK_zgXQ |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=Novel+piperazine+salts+as+D3%2FD2+antagonists&rft.inventor=AGAINE+CSONGOR%2C+EVA&rft.inventor=GREINER%2C+ISTVAN&rft.inventor=SEBOK%2C+FERENC&rft.inventor=DOMANY%2C+GYORGY&rft.inventor=CZIBULA%2C+LASZLO&rft.date=2010-01-16&rft.externalDBID=A&rft.externalDocID=TW201002323A |