P38 kinase inhibiting agents

Compounds described by the chemical formula (1) or pharmaceutically acceptable salts thereof: are inhibitors of p38 and are useful in the treatment of inflammation such as in the treatment of asthma, COPD, ARDS, rheumatoid arthritis, rheumatoid spondylitis, osteoarthritis, gouty arthritis and other...

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Main Authors CHEN, MENG-HSIN, MEINKE, PETER T, KOYAMA, HIROO, DYKSTRA, KEVIN D, YANG, GINGER XU-QIANG, SAHOO, SOUMYA P, O'KEEFE, STEPHEN J
Format Patent
LanguageChinese
English
Published 16.12.2009
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Abstract Compounds described by the chemical formula (1) or pharmaceutically acceptable salts thereof: are inhibitors of p38 and are useful in the treatment of inflammation such as in the treatment of asthma, COPD, ARDS, rheumatoid arthritis, rheumatoid spondylitis, osteoarthritis, gouty arthritis and other arthritic conditions; inflamed joints, eczema, psoriasis or other inflammatory skin conditions such as sunburn; inflammatory eye conditions including conjunctivitis; pyresis, pain and other conditions associated with inflammation.
AbstractList Compounds described by the chemical formula (1) or pharmaceutically acceptable salts thereof: are inhibitors of p38 and are useful in the treatment of inflammation such as in the treatment of asthma, COPD, ARDS, rheumatoid arthritis, rheumatoid spondylitis, osteoarthritis, gouty arthritis and other arthritic conditions; inflamed joints, eczema, psoriasis or other inflammatory skin conditions such as sunburn; inflammatory eye conditions including conjunctivitis; pyresis, pain and other conditions associated with inflammation.
Author O'KEEFE, STEPHEN J
CHEN, MENG-HSIN
KOYAMA, HIROO
SAHOO, SOUMYA P
YANG, GINGER XU-QIANG
MEINKE, PETER T
DYKSTRA, KEVIN D
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– fullname: SAHOO, SOUMYA P
– fullname: O'KEEFE, STEPHEN J
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Snippet Compounds described by the chemical formula (1) or pharmaceutically acceptable salts thereof: are inhibitors of p38 and are useful in the treatment of...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title P38 kinase inhibiting agents
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