Azaindole inhibitors of aurora kinases

The present invention relates to a compound represented by Formula (I): and pharmaceutically acceptable salts. Compounds of the present invention inhibit Aurora kinase, making them especially suitable for the treatment of a number of diseases, including solid tumor cancers and hematological cancers.

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Bibliographic Details
Main Authors DHANAK, DASHYANT, NEWLANDER, KENNETH ALLEN, TANG, JUN, ADAMS, JERRY LEROY, AXTEN, JEFFREY MICHAEL, PARRISH, CYNTHIA A, CHAUDHARI, AMITA M, HAMAJIMA, TOSHIHIRO, SARPONG, MARTHA A, SILVA, DOMINGOS, ADAMS, NICHOLAS D
Format Patent
LanguageChinese
English
Published 01.01.2008
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to a compound represented by Formula (I): and pharmaceutically acceptable salts. Compounds of the present invention inhibit Aurora kinase, making them especially suitable for the treatment of a number of diseases, including solid tumor cancers and hematological cancers.
Bibliography:Application Number: TW200695148066