Process for producing aminopyrrolidine derivative and intermediate compound

This invention discloses a process for industrially producing an aminopyrrolidine derivative represented by the following formula, which has antagonistic activity against a chemokine receptor; an intermediate; and a process for producing the intermediate. In the formula R11 is a hydrogen, C1-6 alkyl...

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Main Authors KOGA, MASAHIRO, SATO, YOSHINORI, TAKEYASU, TAKUMI, ASAHITA, MITSUHARU, IMAI, MINORU, KAWANA, ASAHI, SAKAI, MITSURU, MANABE, KENJI, MATSUMOTO, YOSHIYUKI, TAKEUCHI, SUSUMU
Format Patent
LanguageChinese
English
Published 01.06.2005
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:This invention discloses a process for industrially producing an aminopyrrolidine derivative represented by the following formula, which has antagonistic activity against a chemokine receptor; an intermediate; and a process for producing the intermediate. In the formula R11 is a hydrogen, C1-6 alkyl, or C2-7 alkanoyl group; R12, R14, R15, R16, and R17, each is a hydrogen, halogeno, optionally halogenated C1-6 alkyl, optionally halogenated C1-6 alkoxy, hydroxy, or C2-7 alkoxycarbonyl group; R23, R24, R25, and R26 each is a hydrogen, halogeno, optionally halogenated C1-6 alkyl, optionally halogenated C1-6 alkoxy, or hydroxy group; and R3 is a hydrogen or C1-6 alkyl group.
Bibliography:Application Number: TW200493130663