Benzopyran compounds for use in the treatment and prevention of inflammation related conditions

The subject invention concerns methods and compounds that have utility in the treatment of a condition associated with cyclooxygenase-2 mediated disorders. Compounds of particular interest are benzopyrans and their analogs defined by formula 1, Wherein Z, X, R1, R2, R3, and R4 are as described in th...

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Main Authors YU, YI, KOSZYK, FRANCIS, LIMBURG, DAVID, TSYMBALOV, SOFYA, KIEFER, JR, ASTON, KARL W, WANG, LIJUAN JANE, CARTER, JEFFREY S, SPRINGER, JOHN R, HUFF, RENEE M, DEPROW, ANGELA M, XING, LI, LIAO, SUBO, BROWN, DAVID L, HALLINAN, E. ANN, FLETCHER, THERESA R, KRAMER, STEVEN W, HAMPER, BRUCE C
Format Patent
LanguageChinese
English
Published 01.02.2005
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The subject invention concerns methods and compounds that have utility in the treatment of a condition associated with cyclooxygenase-2 mediated disorders. Compounds of particular interest are benzopyrans and their analogs defined by formula 1, Wherein Z, X, R1, R2, R3, and R4 are as described in the specification.
Bibliography:Application Number: TW200493108361