Substituted pyridines and pyridazines with angiogenesis inhibiting activity

• Main Authors: SU NING, KLUENDER HAROLD C. E, LEE WENDY, JOE TEDDY KITE, DUMAS JACQUES P, BOYER STEPHEN JAMES, NAGARATHNAM DHANAPALAN, SIBLEY ROBERT N, DIXON JULIE A
• Format: Patent
• Language: English; Slovak
• Published: 07.09.2010
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

Substituted pyridines and pyridazines having angiogenesis inhibiting activity and generalized structural formula (I) wherein the ring containing A, B, D, E, and L is phenyl or a nitrogen-containing heterocycle; groups X and Y may be any of a variety of defined linking units; R1 and R2 may be defined...