NOVEL ANTITUMOR AND ANTILEUKEMIA SUBSTANCES, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME
PCT No. PCT/FR95/00814 Sec. 371 Date Dec. 19, 1996 Sec. 102(e) Date Dec. 19, 1996 PCT Filed Jun. 20, 1995 PCT Pub. No. WO96/00205 PCT Pub. Date Jan. 4, 1996(3-hydroxy-4-methoxybenzyl)-7-methylene-1-vinyl-2,3,3a,4,7,7a-hexahydroinden-4-one of formula (I): (I) and 3-(3-hydroxy-4-methoxybenzyl)-4-hydro...
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| Main Authors | , |
|---|---|
| Format | Patent |
| Language | English |
| Published |
04.06.1997
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| Edition | 6 |
| Subjects | |
| Online Access | Get full text |
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| Abstract | PCT No. PCT/FR95/00814 Sec. 371 Date Dec. 19, 1996 Sec. 102(e) Date Dec. 19, 1996 PCT Filed Jun. 20, 1995 PCT Pub. No. WO96/00205 PCT Pub. Date Jan. 4, 1996(3-hydroxy-4-methoxybenzyl)-7-methylene-1-vinyl-2,3,3a,4,7,7a-hexahydroinden-4-one of formula (I): (I) and 3-(3-hydroxy-4-methoxybenzyl)-4-hydroxy-7-methyl-1-vinylindan of formula (II): (II) as well as their stereoisomeric forms are disclosed. Also disclosed are a process for producing these compounds from the plant Ottelia alismoides and pharmaceutical compositions containing them. The novel compounds of formulas (I) and (II) have remarkable antitumor and antileukaemic properties. |
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| AbstractList | PCT No. PCT/FR95/00814 Sec. 371 Date Dec. 19, 1996 Sec. 102(e) Date Dec. 19, 1996 PCT Filed Jun. 20, 1995 PCT Pub. No. WO96/00205 PCT Pub. Date Jan. 4, 1996(3-hydroxy-4-methoxybenzyl)-7-methylene-1-vinyl-2,3,3a,4,7,7a-hexahydroinden-4-one of formula (I): (I) and 3-(3-hydroxy-4-methoxybenzyl)-4-hydroxy-7-methyl-1-vinylindan of formula (II): (II) as well as their stereoisomeric forms are disclosed. Also disclosed are a process for producing these compounds from the plant Ottelia alismoides and pharmaceutical compositions containing them. The novel compounds of formulas (I) and (II) have remarkable antitumor and antileukaemic properties. |
| Author | LEBOUL JEAN PROVOST JEAN |
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| Title | NOVEL ANTITUMOR AND ANTILEUKEMIA SUBSTANCES, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME |
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