Combined telomerase inhibitor and gemcitabine for the treatment of cancer
A method and kit for inhibiting the proliferation of cancer cells are disclosed, based on a combination of a gemcitabine and a telomerase inhibitor. When used in cancer therapy, the two compounds in combination enhance the anti-cancer treatment efficacy obtained with gemcitabine alone or the telomer...
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| Main Authors | , |
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| Format | Patent |
| Language | English Slovenian |
| Published |
31.01.2019
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| Subjects | |
| Online Access | Get full text |
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| Abstract | A method and kit for inhibiting the proliferation of cancer cells are disclosed, based on a combination of a gemcitabine and a telomerase inhibitor. When used in cancer therapy, the two compounds in combination enhance the anti-cancer treatment efficacy obtained with gemcitabine alone or the telomerase inhibitor alone. Preferably, efficacy is supraadditive or synergistic in nature relative to the combined effects of the individual agents, with minimal exacerbation of side effects. |
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| AbstractList | A method and kit for inhibiting the proliferation of cancer cells are disclosed, based on a combination of a gemcitabine and a telomerase inhibitor. When used in cancer therapy, the two compounds in combination enhance the anti-cancer treatment efficacy obtained with gemcitabine alone or the telomerase inhibitor alone. Preferably, efficacy is supraadditive or synergistic in nature relative to the combined effects of the individual agents, with minimal exacerbation of side effects. |
| Author | Go Ning Tressler Robert J |
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| DocumentTitleAlternate | Kombinirani telomerazni inhibitor in gemcitabin za zdravljenje raka |
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| RelatedCompanies | GERON CORPORATION |
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| Snippet | A method and kit for inhibiting the proliferation of cancer cells are disclosed, based on a combination of a gemcitabine and a telomerase inhibitor. When used... |
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| Title | Combined telomerase inhibitor and gemcitabine for the treatment of cancer |
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