URACIL DERIVATIVES AS AXL AND C-MET KINASE INHIBITORS

The present invention provides compounds of Formula I or pharmaceutically acceptable salt forms thereof, wherein R a , R b , R c , R d , D, W, R 1a , R 1b , R 1c , Y, R 3 , X, E and G are as defined herein, and uses as AXL and c-MET kinase inhibitors .

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Bibliographic Details
Main Authors PROUTY Catherine P, HUDKINS Robert L, TRIPATHY Rabindranath, DANDU Reddeppareddy, JOSEF Kurt A
Format Patent
LanguageEnglish
Slovenian
Published 26.04.2017
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Abstract The present invention provides compounds of Formula I or pharmaceutically acceptable salt forms thereof, wherein R a , R b , R c , R d , D, W, R 1a , R 1b , R 1c , Y, R 3 , X, E and G are as defined herein, and uses as AXL and c-MET kinase inhibitors .
AbstractList The present invention provides compounds of Formula I or pharmaceutically acceptable salt forms thereof, wherein R a , R b , R c , R d , D, W, R 1a , R 1b , R 1c , Y, R 3 , X, E and G are as defined herein, and uses as AXL and c-MET kinase inhibitors .
Author HUDKINS Robert L
DANDU Reddeppareddy
JOSEF Kurt A
PROUTY Catherine P
TRIPATHY Rabindranath
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Snippet The present invention provides compounds of Formula I or pharmaceutically acceptable salt forms thereof, wherein R a , R b , R c , R d , D, W, R 1a , R 1b , R...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title URACIL DERIVATIVES AS AXL AND C-MET KINASE INHIBITORS
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