FARNESYLTRANSFERASE INHIBITORS

Substituted imidazoles and thiazoles having the formula are useful for inhibiting farnesyltransferase. Also disclosed are farnesyltransferase-inhibiting compositions and methods of inhibiting farnesyltransferase in a patient.

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Bibliographic Details
Main Authors LIN NAN-HORNG, HASVOLD LISA A, SHAM HING L, MANTEI ROBERT A, TONG YUNSONG, WANG GARY T, ROCKWAY TODD W, WANG LE, WANG WEIBO, LI QUN, LI TOMGMEI, GWALTNEY STEPHEN, SULLIVAN GERARD M, WANG XILU, CLAIBORNE AKIYO K
Format Patent
LanguageEnglish
Slovenian
Published 31.10.2006
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Substituted imidazoles and thiazoles having the formula are useful for inhibiting farnesyltransferase. Also disclosed are farnesyltransferase-inhibiting compositions and methods of inhibiting farnesyltransferase in a patient.
Bibliography:Application Number: SI20010030573T