Use of substituted imidazolidin-2,4-diones as analgesics

The use of substituted imidazolidine-2,4-dione derivatives of formula (I) is claimed for the preparation of a medicament for the treatment of pain. R1 = 1-6C alkyl or 3-6C cycloalkyl; R2 = 1-6C alkyl, phenyl, -(CH2)1-3-Ph or -(CH2)1-4-COOR5; or R1 + R2 = -(CH2)4-6-, -(CH2)2O(CH2)2- or -CH2-o-C6H4-CH...

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Bibliographic Details
Main Authors ZIMMER OSWALD DR, SELVE NORMA DR
Format Patent
LanguageEnglish
Slovenian
Published 31.08.2004
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The use of substituted imidazolidine-2,4-dione derivatives of formula (I) is claimed for the preparation of a medicament for the treatment of pain. R1 = 1-6C alkyl or 3-6C cycloalkyl; R2 = 1-6C alkyl, phenyl, -(CH2)1-3-Ph or -(CH2)1-4-COOR5; or R1 + R2 = -(CH2)4-6-, -(CH2)2O(CH2)2- or -CH2-o-C6H4-CH2-; R3 = H, 1-5C alkyl or -(CH2)1-4-COOR5; R4 = pyridinyl, pyrazinyl, mono- or dimethyl-pyridinyl, R6-substituted thiazolyl, methyl-isoxazolyl, benzo-2,1,3-thiadiazolyl or 5-(R7)-1,3,4-thiadiazol-2-yl; R5 = 1-3C alkyl; R6 = H, 1-4C alkyl, Ph or benzyl; R7 = H, 1-4C alkyl or CF3.
Bibliography:Application Number: SI19980030652T