ESCHERICHIA COLI COMPOSITIONS AND METHODS THEREOF

• Main Authors: ANDERSON, Annaliesa Sybil, KIM, Jin-Hwan, CHORRO, Laurent Oliver, MERCHANT, Nishith, LOMBERK, Scott Ellis, SINGH, Suddham, CHU, Ling, KODALI, Srinivas, CHEN, Wei, PAN, Rosalind, LOTVIN, Jason Arnold, TAKANE, Karen Kiyoko, DONALD, Robert G. K, PRASAD, Avvari Krishna, RUPPEN, Mark Edward, GU, Jianxin, MORAN, Justin Keith
• Format: Patent
• Language: English
• Published: 29.04.2021
• Subjects: CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

In one aspect, the invention relates to an immunogenic composition comprising modified O-polysaccharide molecules derived from E. coli lipopolysaccharides and conjugates thereof. Multivalent vaccines may be prepared by combining two or more monovalent immunogenic compositions for different E. coli s...