ANTIBODY-PYRROLOBENZODIAZEPINE DERIVATIVE CONJUGATE

• Main Authors: TODA Narihiro, IWAMOTO Mitsuhiro, OKAJIMA Daisuke, NAKADA Takashi, HAYAKAWA Ichiro, UCHIDA Hiroaki, MASUDA Takeshi, DOI Fuminao, HARADA Naoya, OTA Yusuke, MEGURO Masaki, NAKAMURA Kensuke, TERAUCHI Tomoko, HAMADA Hirofumi, ASHIDA Shinji
• Format: Patent
• Language: English
• Published: 29.04.2020
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; VINEGAR; WINE

The present invention provides a novel antibody-pyrrolodiazepine derivative and a novel antibody-pyrrolodiazepine derivative conjugate using the same, and a novel CLDN6 and/or CLDN9 antibody.