ANTI-CD3 ANTIBODIES, ANTI-CD123 ANTIBODIES AND BISPECIFIC ANTIBODIES SPECIFICALLY BINDING TO CD3 AND/OR CD123

The present invention concerns antibody-like binding protein specifically binding to CD3 and binding specifically to at least one further antigen, for example CD123. The present invention also concerns antibody-like binding protein specifically binding to CD123 and binding specifically to at least o...

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Main Authors LEUSCHNER, Wulf-Dirk, WONEROW, Peter, CARREZ, Chantal, ALBRECHT, Jana, WETZEL, Marie-Cécile, BARRIERE, Cédric, GUERIF, Stéphane, KROLL, Katja, LANGE, Christian, SCHNEIDER, Marion, BEIL, Christian, LEMOINE, Cendrine, RAO, Ercole, BENINGA, Jochen
Format Patent
LanguageEnglish
Published 30.08.2017
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Abstract The present invention concerns antibody-like binding protein specifically binding to CD3 and binding specifically to at least one further antigen, for example CD123. The present invention also concerns antibody-like binding protein specifically binding to CD123 and binding specifically to at least one further antigen. The invention further concerns anti-CD3 antibodies and anti-CD123 antibodies. The invention also relates to pharmaceutical compositions comprising the antibody-like binding protein, anti-CD3 antibodies or anti-CD123 antibodies of the invention, and their use to treat cancer. The invention further relates to isolated nucleic acids, vectors and host cells comprising a sequence encoding said antibody-like binding protein, anti-CD3 or anti-CD123 antibody and the use of said anti-CD123 antibody as a diagnostic tool.
AbstractList The present invention concerns antibody-like binding protein specifically binding to CD3 and binding specifically to at least one further antigen, for example CD123. The present invention also concerns antibody-like binding protein specifically binding to CD123 and binding specifically to at least one further antigen. The invention further concerns anti-CD3 antibodies and anti-CD123 antibodies. The invention also relates to pharmaceutical compositions comprising the antibody-like binding protein, anti-CD3 antibodies or anti-CD123 antibodies of the invention, and their use to treat cancer. The invention further relates to isolated nucleic acids, vectors and host cells comprising a sequence encoding said antibody-like binding protein, anti-CD3 or anti-CD123 antibody and the use of said anti-CD123 antibody as a diagnostic tool.
Author LANGE, Christian
KROLL, Katja
BEIL, Christian
WONEROW, Peter
ALBRECHT, Jana
SCHNEIDER, Marion
GUERIF, Stéphane
LEMOINE, Cendrine
RAO, Ercole
BENINGA, Jochen
CARREZ, Chantal
BARRIERE, Cédric
LEUSCHNER, Wulf-Dirk
WETZEL, Marie-Cécile
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– fullname: WETZEL, Marie-Cécile
– fullname: BARRIERE, Cédric
– fullname: GUERIF, Stéphane
– fullname: KROLL, Katja
– fullname: LANGE, Christian
– fullname: SCHNEIDER, Marion
– fullname: BEIL, Christian
– fullname: LEMOINE, Cendrine
– fullname: RAO, Ercole
– fullname: BENINGA, Jochen
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Snippet The present invention concerns antibody-like binding protein specifically binding to CD3 and binding specifically to at least one further antigen, for example...
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SubjectTerms CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Title ANTI-CD3 ANTIBODIES, ANTI-CD123 ANTIBODIES AND BISPECIFIC ANTIBODIES SPECIFICALLY BINDING TO CD3 AND/OR CD123
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