SE7500065

6 beta -Acylamino-1-(oxadethia)penicillanic acid compounds are prepared from 6 alpha -acylamino-6 beta -methylthio-1-(oxadethia)penicillanic acid compounds. The process proceeds through the formation of a 6-acylimino intermediate, which is treated using an active hydride to yield the desired 6 beta...

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Bibliographic Details
Main Author CAMA L D
Format Patent
LanguageEnglish
Published 18.07.1975
Subjects
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Abstract 6 beta -Acylamino-1-(oxadethia)penicillanic acid compounds are prepared from 6 alpha -acylamino-6 beta -methylthio-1-(oxadethia)penicillanic acid compounds. The process proceeds through the formation of a 6-acylimino intermediate, which is treated using an active hydride to yield the desired 6 beta -acylamino compound. Novel intermediates are also disclosed. The compounds prepared are useful antibiotics having enhanced activity over penicillanic acid derivatives. The process can also be applied to penicillin derivatives.
AbstractList 6 beta -Acylamino-1-(oxadethia)penicillanic acid compounds are prepared from 6 alpha -acylamino-6 beta -methylthio-1-(oxadethia)penicillanic acid compounds. The process proceeds through the formation of a 6-acylimino intermediate, which is treated using an active hydride to yield the desired 6 beta -acylamino compound. Novel intermediates are also disclosed. The compounds prepared are useful antibiotics having enhanced activity over penicillanic acid derivatives. The process can also be applied to penicillin derivatives.
Author CAMA L D
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Snippet 6 beta -Acylamino-1-(oxadethia)penicillanic acid compounds are prepared from 6 alpha -acylamino-6 beta -methylthio-1-(oxadethia)penicillanic acid compounds....
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SubjectTerms ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Title SE7500065
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