PROTEOLYTICALLY STABLE NONAPEPTIDE CAPABLE OF PREVENTING AN INCREASE IN HYPERPERMEABILITY OF VASCULAR ENDOTHELIUM

• Main Authors: Ovchinnikov Mikhail Vladimirovich, Kazakova Olga Alekseevna, Shirinskij Vladimir Pavlovich, Samsonov Mikhail Vasilevich, Terekhova Olga Aleksandrovna, Khapchaev Asker Yusufovich, Sidorova Mariya Vladimirovna, Bushuev Valerij Nikolaevich, Palkeeva Marina Evgenevna, Azmuko Andrej Andreevich, Arzamastsev Evgenij Veniaminovich, Molokoedov Aleksandr Sergeevich
• Format: Patent
• Language: English; Russian
• Published: 22.03.2019
• Subjects: CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

FIELD: chemistry.SUBSTANCE: invention relates to a low-toxic, proteolytically stable, biologically active nonapeptide of formula H-Lys--Lys-Arg-Ala-Ala-Arg-Ala-Thr-Ser-NH(l). Claimed peptide can be used in medicine as a decongestant.EFFECT: claimed peptide is able to prevent the development of vascu...