CULTURE OF GENETICALLY NON-MODIFIED HUMAN CHONDROPROGENITORY CELLS AND METHOD FOR THEIR PREPARING

FIELD: medicine, traumatology, orthopedics. ^ SUBSTANCE: invention relates to non-modified animal and human cells and methods for their preparing. The culture of genetically non-modified human chondroprogenitory cells obtained from human embryo hyaline cartilage at stage 1-2 trimesters of pregnancy...

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Main Authors REPIN V.S, MAKAROV A.V, RZHANINOVA A.A, FATKHUDINOV T.KH, GOL'DSHTEJN D.V, PULIN A.A, SABURINA I.N, SHAMENKOV D.A, BAZHANOV N.A
Format Patent
LanguageEnglish
Russian
Published 27.12.2004
Edition7
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:FIELD: medicine, traumatology, orthopedics. ^ SUBSTANCE: invention relates to non-modified animal and human cells and methods for their preparing. The culture of genetically non-modified human chondroprogenitory cells obtained from human embryo hyaline cartilage at stage 1-2 trimesters of pregnancy comprises aggrecan- and collagen II-expressing cells in the amount 80%, not less. Suspension of primary dissociated human chondroprogenitory cells is obtained from human embryo cartilage tissue at stage 1-2 trimesters of pregnancy and cultured in selective cultural medium. Invention provides preparing homogenous cell culture for transplantation, enhanced effectiveness of treatment and avoiding undesirable results. ^ EFFECT: improved preparing method. ^ 10 cl, 1 ex
Bibliography:Application Number: RU20030131983