RECOMBINANT PROTEIN COMPOSITION, METHOD FOR PREPARING SUCH COMPOSITION, PHARMACEUTICAL KIT OF REAGENTS FOR IMMUNOTHERAPY AND PROPHYLACTIC VACCINATION OF TUMOR DISEASES IN ANUS-GENITAL SPHERE, METHOD FOR IMMUNOTHERAPY AND PROPHYLACTIC VACCINATION BASED ON THEREOF

FIELD: medicine, pharmacy. SUBSTANCE: invention relates to composition of recombinant proteins, method for preparing the composition, pharmaceutical kit of reagents used in immunotherapy and prophylactic vaccination of tumor diseases in anus-genital sphere and method for immunotherapy and prophylact...

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Bibliographic Details
Main Authors SVESHNIKOV P.G, PAL'TSEV M.A, KISELEV V.I, KISELEV O.I, SEVERIN E.S
Format Patent
LanguageEnglish
Russian
Published 27.05.2004
Edition7
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:FIELD: medicine, pharmacy. SUBSTANCE: invention relates to composition of recombinant proteins, method for preparing the composition, pharmaceutical kit of reagents used in immunotherapy and prophylactic vaccination of tumor diseases in anus-genital sphere and method for immunotherapy and prophylactic vaccination. Invention involves hybrid proteins consisting of amino acid sequences of oncoprotein E7 of human papilloma virus of 16 and 18 types that are bound covalently with amino acid sequence of heat shock protein with molecular mass 70 kDa (Hsp70) from M. tuberculosis - E716-Hsp70 and E718-Hsp70, respectively. EFFECT: enhanced activity of composition. 6 cl, 5 dwg, 7 ex
Bibliography:Application Number: RU20020128131