METHOD FOR PREPARING PROLONGED-ACTION EYE DROPS MADE OF PILOCARPINE HYDROCHLORIDE

FIELD: pharmacology; ophthalmology. SUBSTANCE: first aqueous solution of pilocarpine chloride is prepared in concentration 10-20 wt.p. (all numerical values are given in the rate per 1000 wt.p. of solution). To make solution isotonic sodium chloride taken in the amount 8.8-9.0 wt.p is added to it, f...

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Bibliographic Details
Main Authors KORNILOVA A.A, STEKOL'NIKOV L.I
Format Patent
LanguageEnglish
Published 10.03.1998
Edition6
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:FIELD: pharmacology; ophthalmology. SUBSTANCE: first aqueous solution of pilocarpine chloride is prepared in concentration 10-20 wt.p. (all numerical values are given in the rate per 1000 wt.p. of solution). To make solution isotonic sodium chloride taken in the amount 8.8-9.0 wt.p is added to it, followed by adding to it preservative agent, namely, zinc undecylenate in the amount 0.01-0.02 wt.p. Eye drops additionally contain sodium hyaluronate in the amount 5-10 wt.p. EFFECT: enhanced microbiological stability of pilocarpine hydrochloride eye drops; extended term of their therapeutic effect. 3 tble
Bibliography:Application Number: RU19930042330