CRYSTAL OF PYRIDO[3, 4-D]PYRIMIDINE DERIVATIVE OR SOLVATE THEREOF

Provided is a crystal of a novel pyrido[3, 4-d]pyrimidine derivative having excellent CDK 4/6 inhibitory activity. A crystal of a compound represented by formula (I). In the formula, Rrepresents a hydrogen atom or a Calkyl group; Rrepresents a hydrogen atom or an oxo group; L represents a single bon...

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Main Authors MIYAMOTO, HIDETOSHI, YAJIMA, NAOKI, MIZUNO, TSUYOSHI, UNOKI, GEN, MIYAZAWA, YUKI
Format Patent
LanguageEnglish
Serbian
Published 31.03.2022
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Abstract Provided is a crystal of a novel pyrido[3, 4-d]pyrimidine derivative having excellent CDK 4/6 inhibitory activity. A crystal of a compound represented by formula (I). In the formula, Rrepresents a hydrogen atom or a Calkyl group; Rrepresents a hydrogen atom or an oxo group; L represents a single bond or a Calkylene group; and X represents CH or N.
AbstractList Provided is a crystal of a novel pyrido[3, 4-d]pyrimidine derivative having excellent CDK 4/6 inhibitory activity. A crystal of a compound represented by formula (I). In the formula, Rrepresents a hydrogen atom or a Calkyl group; Rrepresents a hydrogen atom or an oxo group; L represents a single bond or a Calkylene group; and X represents CH or N.
Author UNOKI, GEN
YAJIMA, NAOKI
MIYAZAWA, YUKI
MIYAMOTO, HIDETOSHI
MIZUNO, TSUYOSHI
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DocumentTitleAlternate KRISTAL PIRIDO[3, 4-D]PIRIMIDIN DERIVATA ILI NJEGOV SOLVAT
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RelatedCompanies TEIJIN PHARMA LIMITED
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title CRYSTAL OF PYRIDO[3, 4-D]PYRIMIDINE DERIVATIVE OR SOLVATE THEREOF
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