A TRANSMUCOSAL VETERINARY COMPOSITION COMPRISING DETOMIDINE

Farmaceutska veterinarska smeša u obliku transmukoznog gela sadrži, u odnosu na težinu smeše, 0.1 - 5% (tež/tež) detomidina ili njegove farmaceutski prihvatljive soli;0.3 - 40% (tež/tež) želirajućeg sredstva; 0.2 - 15% (tež/tež) pojačivača penetracije kroz mukozu; 5 - 50% (tež/tež) organskog ko-rast...

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Bibliographic Details
Main Authors LEINO, LASSE, RANTALA, MARIA, KOISTINEN, PIRITTA, AF URSIN, KAIJA, HUHTINEN, MIRJA, KAUKINEN, HELENA
Format Patent
LanguageEnglish
Serbian
Published 30.04.2013
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Farmaceutska veterinarska smeša u obliku transmukoznog gela sadrži, u odnosu na težinu smeše, 0.1 - 5% (tež/tež) detomidina ili njegove farmaceutski prihvatljive soli;0.3 - 40% (tež/tež) želirajućeg sredstva; 0.2 - 15% (tež/tež) pojačivača penetracije kroz mukozu; 5 - 50% (tež/tež) organskog ko-rastvarača koji se meša sa vodom; i 30 - 80% (tež/tež) vode.Prijava sadrži još 22 patentna zahteva. The present invention relates to a veterinary composition in a semisolid form adapted for transmucosal administration for providing sedation and analgesia in large animals such as horses and cattle. The semisolid transmucosal composition of the invention comprises detomidine or a pharmaceutically acceptable salt thereof as an active ingredient. The composition provides a rapid onset of action while having low irritation potential in the oral mucosa.
Bibliography:Application Number: RS2012P000440