NOVO VIRUS MYXOMA RECOMBINANTE ATENUADO E SUA UTILIZACAO PARA A PREPARACAO DE VACINAS MISTAS CONTRA A MIXOMATOSE E CONTRA A DOENCA HEMORRAGICA DOS COELHOS

It is here described a new recombinant myxoma virus deposited in the CNCM with deposit number I-1990, that contains within its genome a nucleotide sequence capable of expressing the antigen protein VP60 of the rabbit hemorrhagic disease virus, which is attenuated and exhibits a controlled transmissi...

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Main Authors JOSE MANUEL SANCHEZ VIZCAINO, MONICA MORALES CAMARZANA, JUAN MARIA TORRES TRILLO, JUAN BARCENA DEL RIEGO, RAFAEL BLASCO LOZANO, FRANCISCO PARRA FERNANDEZ, BELEN VAZQUEZ RUIZ, ALBERT PAGES MANTE
Format Patent
LanguagePortuguese
Published 30.07.2004
Edition7
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
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Summary:It is here described a new recombinant myxoma virus deposited in the CNCM with deposit number I-1990, that contains within its genome a nucleotide sequence capable of expressing the antigen protein VP60 of the rabbit hemorrhagic disease virus, which is attenuated and exhibits a controlled transmission capacity, as well as the combined anti-myxomatosis and anti-RHDV vaccines - self-propagating in a controlled manner - obtained from the aforesaid virus. Also described, is a method for obtaining attenuated recombinant myxoma virus useful in the preparation of self-propagating combined vaccines against myxomatosis and other infectious diseases of leporids.
Bibliography:Application Number: PT19990500099T