PROCESSO PARA A PREPARACAO DE CICLOALCANO{B}DI-HIDROINDOLE-SULFONAMIDAS E CICLOALCANO {B}INDOLE-SULFONAMIDAS, SUBSTITUIDAS POR HETEROCICLOS

• Main Authors: ERWIN BISCHOFF, PETER NORMAN, ULRICH NIEWOHNER, ULRICH ROSENTRETER, NIGEL J. CUTHBERT, ELISABETH PERZBORN, HILARY P. FRANCIS, ULRICH E. MULLER, HANS-GEORG DELLWEG
• Format: Patent
• Language: Portuguese
• Published: 31.01.1992
• Edition: 5
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

Cycloalkano[b]dihydroindoles and -indolesulphonamides substituted by heterocycles can be prepared by reaction of corresponding indoles with acrylonitrile and subsequent hydrolysis of the cyanoethyl compounds or by reaction of corresponding hydrazines with cycloalkanones. The cycloalkano[b]dihydroind...