PROCESSO PARA A PREPARACAO DE CICLOALCANO{B}DI-HIDROINDOLE-SULFONAMIDAS E CICLOALCANO {B}INDOLE-SULFONAMIDAS, SUBSTITUIDAS POR HETEROCICLOS

Cycloalkano[b]dihydroindoles and -indolesulphonamides substituted by heterocycles can be prepared by reaction of corresponding indoles with acrylonitrile and subsequent hydrolysis of the cyanoethyl compounds or by reaction of corresponding hydrazines with cycloalkanones. The cycloalkano[b]dihydroind...

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Main Authors ERWIN BISCHOFF, PETER NORMAN, ULRICH NIEWOHNER, ULRICH ROSENTRETER, NIGEL J. CUTHBERT, ELISABETH PERZBORN, HILARY P. FRANCIS, ULRICH E. MULLER, HANS-GEORG DELLWEG
Format Patent
LanguagePortuguese
Published 31.01.1992
Edition5
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Abstract Cycloalkano[b]dihydroindoles and -indolesulphonamides substituted by heterocycles can be prepared by reaction of corresponding indoles with acrylonitrile and subsequent hydrolysis of the cyanoethyl compounds or by reaction of corresponding hydrazines with cycloalkanones. The cycloalkano[b]dihydroindoles and -indolesulphonamides substituted by heterocycles can be used as active compounds in medicaments, in particular for the treatment of thromboembolisms, ischaemias, asthma and allergies.
AbstractList Cycloalkano[b]dihydroindoles and -indolesulphonamides substituted by heterocycles can be prepared by reaction of corresponding indoles with acrylonitrile and subsequent hydrolysis of the cyanoethyl compounds or by reaction of corresponding hydrazines with cycloalkanones. The cycloalkano[b]dihydroindoles and -indolesulphonamides substituted by heterocycles can be used as active compounds in medicaments, in particular for the treatment of thromboembolisms, ischaemias, asthma and allergies.
Author ULRICH E. MULLER
ERWIN BISCHOFF
NIGEL J. CUTHBERT
HILARY P. FRANCIS
PETER NORMAN
HANS-GEORG DELLWEG
ULRICH ROSENTRETER
ELISABETH PERZBORN
ULRICH NIEWOHNER
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– fullname: ELISABETH PERZBORN
– fullname: HILARY P. FRANCIS
– fullname: ULRICH E. MULLER
– fullname: HANS-GEORG DELLWEG
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Snippet Cycloalkano[b]dihydroindoles and -indolesulphonamides substituted by heterocycles can be prepared by reaction of corresponding indoles with acrylonitrile and...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title PROCESSO PARA A PREPARACAO DE CICLOALCANO{B}DI-HIDROINDOLE-SULFONAMIDAS E CICLOALCANO {B}INDOLE-SULFONAMIDAS, SUBSTITUIDAS POR HETEROCICLOS
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