PROCESS FOR THE PREPARATION OF MIXTURES OF TRIFLUOROACETYL GLATIRAMER ACETATE USING PURIFIED HYDROBROMIC ACID

The Subject invention provides an improved process for obtaining a mixture of polypeptides having nonuniform amino acid sequences, where each polypeptide consists essentially of alanine, glutamic acid, tyrosine and lysine where the resulting mixture of polypeptides comprises less than 0.3% brominate...

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Bibliographic Details
Main Author BEN-ZION DOLITZKY
Format Patent
LanguageEnglish
Portuguese
Published 19.03.2012
Subjects
CHEMISTRY
COMPOSITIONS BASED THEREON
MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
METALLURGY
ORGANIC CHEMISTRY
ORGANIC MACROMOLECULAR COMPOUNDS
PEPTIDES
THEIR PREPARATION OR CHEMICAL WORKING-UP
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Summary:The Subject invention provides an improved process for obtaining a mixture of polypeptides having nonuniform amino acid sequences, where each polypeptide consists essentially of alanine, glutamic acid, tyrosine and lysine where the resulting mixture of polypeptides comprises less than 0.3% brominated tyrosine and less than 1000 ppm metal ion impurities.
Bibliography:Application Number: PT20100150124T