NEW BENZAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS

The present invention relates to new phenylsulfamoyl benzamide derivatives of formula (I) wherein R1-R5 and Z are as defined in the claims, and optical antipodes or racemates and/or salts and/or hydrates and/or solvates thereof, which are selective antagonists of bradykinin B1, to processes for prod...

Full description

Saved in:
Bibliographic Details
Main Authors MONIKA VASTAG, ISTVAN VAGO, GYULA BEKE, SANDOR FARKAS, GYOERGY KESERUE, KATALIN HORNOK, EVA SCHMIDT, EVA BOZO, EVA SZENTIRMAY
Format Patent
LanguageEnglish
Portuguese
Published 06.09.2013
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:The present invention relates to new phenylsulfamoyl benzamide derivatives of formula (I) wherein R1-R5 and Z are as defined in the claims, and optical antipodes or racemates and/or salts and/or hydrates and/or solvates thereof, which are selective antagonists of bradykinin B1, to processes for producing these compounds, to pharmacological compositions containing them and to their use in therapy or prevention of painful and inflammatory conditions.
Bibliography:Application Number: PT20070824994T