AMINOPIRIMIDINAS SUBSTITUIDAS E PROCESSO PARA A SUA PREPARACAO

• Main Authors: MADELENE NIKAIDO, DIMITRIOS SARANTAKIS, JAMES JACOB BICKSLER, JOHN WATSON ELLINGBOE
• Format: Patent
• Language: Portuguese
• Published: 30.07.1999
• Edition: 6
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

This invention relates to substituted 4-aminopyrimidines, which by virtue of their ability to antagonize angiotensin II are useful for the treatment of hypertension, congestive heart failure, and restenosis. The compounds are also useful for reducing lipid levels in the blood plasma and are thus use...