Polymer conjugates with cytokines, chemokines, growth factors, polypeptide hormones and their antagonists, the pharmaceutical composition and method of prevention, diagnosis or treatment

• Main Authors: SAIFER MARK, BHASKARAN SHYAM S, WILLIAMS DAVID L, SHERMAN MERRY
• Format: Patent
• Language: English; Polish
• Published: 19.12.2011
• Subjects: CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

Methods are provided for the synthesis of polymer conjugates of cytokines, chemokines, growth factors, polypeptide hormones and receptor-binding antagonists thereof, which conjugates retain unusually high receptor-binding activity. Preparation of polymer conjugates according to the methods of the pr...