ANTIPICORNAVIRAL COMPOUNDS AND COMPOSITIONS, THEIR PHARMACEUTICAL USES, AND MATERIALS FOR THEIR SYNTHESIS
Compounds of the formula: where the formula variables are as defined in the disclosure, advantageously inhibit or block the biological activity of the picomaviral 3C protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or host...
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| Main Authors | , , , , , , , , , |
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| Format | Patent |
| Language | English Polish |
| Published |
10.01.2005
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| Edition | 7 |
| Subjects | |
| Online Access | Get full text |
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| Abstract | Compounds of the formula: where the formula variables are as defined in the disclosure, advantageously inhibit or block the biological activity of the picomaviral 3C protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with one or more picornaviruses, such as RVP. Intermediates and synthetic methods for preparing such compounds are also described. |
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| AbstractList | Compounds of the formula: where the formula variables are as defined in the disclosure, advantageously inhibit or block the biological activity of the picomaviral 3C protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with one or more picornaviruses, such as RVP. Intermediates and synthetic methods for preparing such compounds are also described. |
| Author | JOHNSON THEODORE O.JR HUA YE CHU SHAO SONG EASTMAN BRIAN WALTER HENDRICKSON THOMAS F SKALITZKY DONALD JAMES LUU HIEP THE YANG YI CHAN FORA P REICH SIEGFRIED HEINZ |
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| DocumentTitleAlternate | Związki i środki przeciwpikornawirusowe, ich zastosowanie farmaceutyczne i substancje do ich syntezy |
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| RelatedCompanies | AGOURON PHARMACEUTICALS,INC |
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| Snippet | Compounds of the formula: where the formula variables are as defined in the disclosure, advantageously inhibit or block the biological activity of the... |
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| SubjectTerms | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| Title | ANTIPICORNAVIRAL COMPOUNDS AND COMPOSITIONS, THEIR PHARMACEUTICAL USES, AND MATERIALS FOR THEIR SYNTHESIS |
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