CATALYTIC PROCESS FOR THE PREPARATION OF THIAZOLE DERIVATIVES

• Main Authors: DESPONDS OLIVIER, RAPOLD THOMAS, GRESSLY REMY, PASSAFARO MARCO, FABER DOMINIK
• Format: Patent
• Language: English; Polish
• Published: 15.11.2004
• Edition: 7
• Subjects: APPARATUS THEREFOR; CHEMISTRY; GENERAL METHODS OF ORGANIC CHEMISTRY; HETEROCYCLIC COMPOUNDS; METALLURGY; ORGANIC CHEMISTRY

A process for the preparation of a compound of formula (I) wherein Q is CH or N; Y is NO2 or CN; Z is CHR3, O, NR3 or S; R1 and R2 are C1-C8 alkyl or together form an alkylene bridge having two or three carbon atoms; by reacting a compound of formula H2C=C(X)CH2NCS wherein X is a leaving group, with...