ISOXAZOLE HYDROXAMIC ACID COMPOUNDS AS LPXC INHIBITORS

This invention pertains generally to compounds of Formula I as described herein and compositions containing such compounds, as well as methods of using such compounds to treat bacterial infections. In certain aspects, the invention provides methods and compositions comprising these compounds for tre...

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Bibliographic Details
Main Authors MADERA, ANN MARIE, KARUR, SUBRAMANIAN, LAPOINTE, GUILLAUME, SWEENEY, ZACHARY KEVIN, FU, JIPING, JIN, XIANMING
Format Patent
LanguageEnglish
Polish
Published 30.04.2020
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:This invention pertains generally to compounds of Formula I as described herein and compositions containing such compounds, as well as methods of using such compounds to treat bacterial infections. In certain aspects, the invention provides methods and compositions comprising these compounds for treating infections caused by Gram-negative bacteria.
Bibliography:Application Number: PL20150816893T