TAMPER-RESISTANT DOSAGE FORM FOR OXIDATION-SENSITIVE OPIOIDS
The invention relates to a thermoformed pharmaceutical dosage form having a breaking strength of at least 300 N, said dosage form comprising - an opioid (A), - a free physiologically acceptable acid (B) in an amount of from 0.001 to 5.0 wt.-%, based on the total weight of the pharmaceutical dosage f...
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| Main Authors | , , , , |
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| Format | Patent |
| Language | English Polish |
| Published |
28.06.2019
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| Subjects | |
| Online Access | Get full text |
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| Abstract | The invention relates to a thermoformed pharmaceutical dosage form having a breaking strength of at least 300 N, said dosage form comprising
- an opioid (A),
- a free physiologically acceptable acid (B) in an amount of from 0.001 to 5.0 wt.-%, based on the total weight of the pharmaceutical dosage form, and
- a polyalkylene oxide (C) having a weight average molecular weight M w of at least 200,000 g/mol. |
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| AbstractList | The invention relates to a thermoformed pharmaceutical dosage form having a breaking strength of at least 300 N, said dosage form comprising
- an opioid (A),
- a free physiologically acceptable acid (B) in an amount of from 0.001 to 5.0 wt.-%, based on the total weight of the pharmaceutical dosage form, and
- a polyalkylene oxide (C) having a weight average molecular weight M w of at least 200,000 g/mol. |
| Author | BICANE, FATIMA BARTHOLOMÄUS, JOHANNES GRIESSMANN, KORNELIA BERTRAM, ULRIKE GEISSLER, ANJA |
| Author_xml | – fullname: GRIESSMANN, KORNELIA – fullname: GEISSLER, ANJA – fullname: BARTHOLOMÄUS, JOHANNES – fullname: BERTRAM, ULRIKE – fullname: BICANE, FATIMA |
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| DocumentTitleAlternate | ODPORNA NA MANIPULACJE POSTAĆ DAWKOWANIA OPIOIDÓW WRAŻLIWYCH NA UTLENIANIE |
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| Notes | Application Number: PL20150184885T |
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| PublicationDateYYYYMMDD | 2019-06-28 |
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| PublicationYear | 2019 |
| RelatedCompanies | Grünenthal GmbH |
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| Snippet | The invention relates to a thermoformed pharmaceutical dosage form having a breaking strength of at least 300 N, said dosage form comprising
- an opioid (A),
-... |
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| SubjectTerms | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| Title | TAMPER-RESISTANT DOSAGE FORM FOR OXIDATION-SENSITIVE OPIOIDS |
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