FACTOR VIII-FC CHIMERIC AND HYBRID POLYPEPTIDES, AND METHODS OF USE THEREOF

• Main Authors: BITONTI, ALAN J, LUK, ALVIN, JIANG, HAIYAN, NUGENT, Karen, OTTMER, MATT, PETERS, ROBERT, DUMONT, JENNIFER A, LI, LIAN, LOW, SUSAN, PIERCE, GLENN, SOMMER, JURG, MCKINNEY, BYRON
• Format: Patent
• Language: English; Polish
• Published: 29.06.2018
• Subjects: CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention provides methods of administering Factor VIII; methods of administering chimeric and hybrid polypeptides comprising Factor VIII; chimeric and hybrid polypeptides comprising Factor VIII; polynucleotides encoding such chimeric and hybrid polypeptides; cells comprising such polynu...