THIAZOLE PYRAZOLOPYRIMIDINES AS CRF1 RECEPTOR ANTAGONISTS

• Main Authors: HIPSKIND, PHILIP ARTHUR, MYERS, JASON KENNETH, CHEN, ZHAOGEN, TAKAKUWA, TAKAKO, HEMBRE, ERIK JAMES, TOTH, JAMES LEE, HAMDOUCHI, CHAFIQ HAMDOUCHI
• Format: Patent
• Language: English; Polish
• Published: 28.02.2011
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention relates to compounds of Formula (I), pharmaceutical compositions thereof, and use thereof as corticotropin releasing factor 1 (CRF1) receptor antagonists in the treatment of psychiatric and neuroendocrine disorders, neurological diseases, and metabolic syndrome.