PYRIDO (2, 3-D) PYRIMIDIN0NE COMPOUNDS AND THEIR USE AS PI3 INHIBITORS

The present invention is directed to novel 4-methylpyridopyrimidinone compounds of Formula (I), and to salts thereof, their synthesis, and their use as inhibitors of phosphoinositide 3-kinase alpha (PI3-Kalpha).

Saved in:
Bibliographic Details
Main Authors KANIA, ROBERT STEVEN, PLEWE, MICHAEL BRUNO, DRESS, KLAUS RUPRECHT, BHUMRALKAR, DILIP, HOFFMAN, JACQUI ELIZABET, LE, PHUONG THI QUY, CHENG, HENGMIAO, TRAN, KHANH TUAN, JOHNSON, MARY CATHERINE, NAMBU, MITCHELL DAVID, PAIRISH, MASON ALAN
Format Patent
LanguageEnglish
Polish
Published 31.10.2011
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

Abstract The present invention is directed to novel 4-methylpyridopyrimidinone compounds of Formula (I), and to salts thereof, their synthesis, and their use as inhibitors of phosphoinositide 3-kinase alpha (PI3-Kalpha).
AbstractList The present invention is directed to novel 4-methylpyridopyrimidinone compounds of Formula (I), and to salts thereof, their synthesis, and their use as inhibitors of phosphoinositide 3-kinase alpha (PI3-Kalpha).
Author BHUMRALKAR, DILIP
JOHNSON, MARY CATHERINE
TRAN, KHANH TUAN
PLEWE, MICHAEL BRUNO
HOFFMAN, JACQUI ELIZABET
PAIRISH, MASON ALAN
DRESS, KLAUS RUPRECHT
KANIA, ROBERT STEVEN
NAMBU, MITCHELL DAVID
LE, PHUONG THI QUY
CHENG, HENGMIAO
Author_xml – fullname: KANIA, ROBERT STEVEN
– fullname: PLEWE, MICHAEL BRUNO
– fullname: DRESS, KLAUS RUPRECHT
– fullname: BHUMRALKAR, DILIP
– fullname: HOFFMAN, JACQUI ELIZABET
– fullname: LE, PHUONG THI QUY
– fullname: CHENG, HENGMIAO
– fullname: TRAN, KHANH TUAN
– fullname: JOHNSON, MARY CATHERINE
– fullname: NAMBU, MITCHELL DAVID
– fullname: PAIRISH, MASON ALAN
BookMark eNrjYmDJy89L5WRwC4gM8nTxV9Aw0lEw1nXRVADxfT1dPP0M_FwVnP19A_xD_VyCFRz9XBRCPFw9gxRCg10VHIMVAjyNFTz9PDydPEP8g4J5GFjTEnOKU3mhNDeDoptriLOHbmpBfnxqcUFicmpeakl8gI-RgbmJoZFRSIixMTFqAFW4LYo
ContentType Patent
DBID EVB
DatabaseName esp@cenet
DatabaseTitleList
Database_xml – sequence: 1
  dbid: EVB
  name: esp@cenet
  url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP
  sourceTypes: Open Access Repository
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
Chemistry
Sciences
DocumentTitleAlternate Związki pirydo(2,3-D)pirymidynonowe i ich zastosowanie jako inhibitory PI3
ExternalDocumentID PL2074122TT3
GroupedDBID EVB
ID FETCH-epo_espacenet_PL2074122TT33
IEDL.DBID EVB
IngestDate Fri Jul 19 13:59:03 EDT 2024
IsOpenAccess true
IsPeerReviewed false
IsScholarly false
Language English
Polish
LinkModel DirectLink
MergedId FETCHMERGED-epo_espacenet_PL2074122TT33
Notes Application Number: PL20070804890T
OpenAccessLink https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20111031&DB=EPODOC&CC=PL&NR=2074122T3
ParticipantIDs epo_espacenet_PL2074122TT3
PublicationCentury 2000
PublicationDate 20111031
PublicationDateYYYYMMDD 2011-10-31
PublicationDate_xml – month: 10
  year: 2011
  text: 20111031
  day: 31
PublicationDecade 2010
PublicationYear 2011
RelatedCompanies Pfizer Products Inc
RelatedCompanies_xml – name: Pfizer Products Inc
Score 2.8311481
Snippet The present invention is directed to novel 4-methylpyridopyrimidinone compounds of Formula (I), and to salts thereof, their synthesis, and their use as...
SourceID epo
SourceType Open Access Repository
SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title PYRIDO (2, 3-D) PYRIMIDIN0NE COMPOUNDS AND THEIR USE AS PI3 INHIBITORS
URI https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20111031&DB=EPODOC&locale=&CC=PL&NR=2074122T3
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3dS8MwED_mFPVNp6LzgwhSFCxuSbvNhyFb09LImpa2k_k0ljaDgWzFVfz3TcuqvuhbkoPjcnD5HZf7ALiZmS2BzVTobbMndYPIVJ8JgfV5T6GFxAkxylmHHu-4Y-N5Yk5qsKhqYco-oZ9lc0RlUYmy97x8r7OfIBYtcyvXD2KhjlZPTtynWlqF-4qpBRod9u3Ap76lWVY_GGk8VDQFnRjHZAu2lRfdLbK_7JdhUZSS_UYU5wB2AsVsmR9CLXtrwJ5VDV5rwK63-e9Wy43prY_ACV5DRn10i-8R0ekdKvYeo4y3uI0s3wv8MacRGnCKYtdmIRpHNhpEKGAEMe6yIYv9MDqGa8eOLVdXAk2_Lz8NRpXoMSEnUF-ulvIUkJGSduFLzIV8VCA7n3VlopAFtzpYJKRrnkHzbz7N_4jnsI83eW6kfQH1_P1DXirgzcVVqbIvzeyAYw
link.rule.ids 230,309,783,888,25578,76884
linkProvider European Patent Office
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3dS8MwED_mFOebTkXnVwQpCha3pN3mw5CtaWm0TUvbjfk0lraDgWzDVfz3TcuqvuhbkoPjcnD5HZf7ALiZ6k2B9USoLb2bqhpJE3UqBFZnXYkWKY6JVsw6dHnbHmrPY31cgXlZC1P0Cf0smiNKi4qlvWfFe736CWLRIrdy_SDm8mj5ZEU9qiRluC-fWqDQQc_0PeoZimH0fEfhgaRJ6MQ4IluwLT3sbt5m3xwN8qKU1W9EsfZhx5fMFtkBVFZvdagZ5eC1Ouy6m_9uudyY3voQLP81YNRDt_geEZXeoXzvMsp4k5vI8FzfG3Iaoj6nKLJNFqBhaKJ-iHxGEOM2G7DIC8IjuLbMyLBVKdDk-_IT3ylFjwg5hupiuUhPAGkJaeW-xEykjxJkZ9NOGktkwc02FjHp6KfQ-JtP4z_iFdTsyHUmDuMvZ7CHNzlvpHUO1ez9I72QIJyJy0J9X_vGg1M
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=PYRIDO+%282%2C+3-D%29+PYRIMIDIN0NE+COMPOUNDS+AND+THEIR+USE+AS+PI3+INHIBITORS&rft.inventor=KANIA%2C+ROBERT+STEVEN&rft.inventor=PLEWE%2C+MICHAEL+BRUNO&rft.inventor=DRESS%2C+KLAUS+RUPRECHT&rft.inventor=BHUMRALKAR%2C+DILIP&rft.inventor=HOFFMAN%2C+JACQUI+ELIZABET&rft.inventor=LE%2C+PHUONG+THI+QUY&rft.inventor=CHENG%2C+HENGMIAO&rft.inventor=TRAN%2C+KHANH+TUAN&rft.inventor=JOHNSON%2C+MARY+CATHERINE&rft.inventor=NAMBU%2C+MITCHELL+DAVID&rft.inventor=PAIRISH%2C+MASON+ALAN&rft.date=2011-10-31&rft.externalDBID=T3&rft.externalDocID=PL2074122TT3