HETEROAROMATIC QUINOLINE COMPOUNDS AND THEIR USE AS PDE10 INHIBITORS
The invention pertains to heteroaromatic compounds that serve as effective phosphodiesterase (PDE) inhibitors. In particular, the invention relates to said compounds which are selective inhibitors of PDE10. The invention also relates to intermediates for preparation of said compounds; pharmaceutical...
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| Main Authors | , , , |
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| Format | Patent |
| Language | English Polish |
| Published |
29.10.2010
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| Subjects | |
| Online Access | Get full text |
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| Abstract | The invention pertains to heteroaromatic compounds that serve as effective phosphodiesterase (PDE) inhibitors. In particular, the invention relates to said compounds which are selective inhibitors of PDE10. The invention also relates to intermediates for preparation of said compounds; pharmaceutical compositions comprising said compounds; and the use of said compounds in a method for treating certain central nervous system (CNS) or other disorders. |
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| AbstractList | The invention pertains to heteroaromatic compounds that serve as effective phosphodiesterase (PDE) inhibitors. In particular, the invention relates to said compounds which are selective inhibitors of PDE10. The invention also relates to intermediates for preparation of said compounds; pharmaceutical compositions comprising said compounds; and the use of said compounds in a method for treating certain central nervous system (CNS) or other disorders. |
| Author | HELAL, CHRISTOPHER JOHN VERHOEST, PATRICK ROBERT HUMPHREY, JOHN MICHAEL HOOVER, DENNIS JAY |
| Author_xml | – fullname: VERHOEST, PATRICK ROBERT – fullname: HELAL, CHRISTOPHER JOHN – fullname: HOOVER, DENNIS JAY – fullname: HUMPHREY, JOHN MICHAEL |
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| DocumentTitleAlternate | Heteroaromatyczne związki chinoliny i ich zastosowanie jako inhibitorów PDE10 |
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| RelatedCompanies | Pfizer Products Inc |
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| Snippet | The invention pertains to heteroaromatic compounds that serve as effective phosphodiesterase (PDE) inhibitors. In particular, the invention relates to said... |
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| SubjectTerms | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| Title | HETEROAROMATIC QUINOLINE COMPOUNDS AND THEIR USE AS PDE10 INHIBITORS |
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