HETEROARYLPHENOXY BENZAMIDE KAPPA OPIOID LIGANDS

• Main Authors: MENTE, Scot Richard, BRODNEY, Michael Aaron, KAUFFMAN, Gregory Wayne, MONTGOMERY, Justin Ian, VERHOEST, Patrick Robert, DUNN, Matthew Francis, RANKIC, Danica Antonia, ROGERS, Bruce Nelsen, ARORA, Kapildev Kashmirilal, GREEN, Michael Eric, KABLAOUI, Natasha Mariam
• Format: Patent
• Language: English
• Published: 11.12.2019
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention provides compounds of Formula I: and pharmaceutically acceptable salts thereof wherein the variables R1, R2, R3, R4, R9, X, m and n are as defined herein; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compound s or...