COMBINATION COMPRISING EP4 ANTAGONIST AND IMMUNE CHECKPOINT INHIBITOR
The present invention addresses the problem of discovering an effective cancer therapy method and providing a medicine. Provided is a medicine comprising a combination of a compound represented by general formula (I), a salt, solvate or N-oxide of the compound or a prodrug of the compound or the sal...
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| Main Authors | , , |
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| Format | Patent |
| Language | English |
| Published |
21.10.2019
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| Subjects | |
| Online Access | Get full text |
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| Abstract | The present invention addresses the problem of discovering an effective cancer therapy method and providing a medicine. Provided is a medicine comprising a combination of a compound represented by general formula (I), a salt, solvate or N-oxide of the compound or a prodrug of the compound or the salt, solvate or N-oxide and an immune checkpoint inhibitor (e.g., an anti-PD-1 antibody). The combination according to the present invention exhibits a high anti-tumor effect and is therefore useful for the treatment of cancer. |
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| AbstractList | The present invention addresses the problem of discovering an effective cancer therapy method and providing a medicine. Provided is a medicine comprising a combination of a compound represented by general formula (I), a salt, solvate or N-oxide of the compound or a prodrug of the compound or the salt, solvate or N-oxide and an immune checkpoint inhibitor (e.g., an anti-PD-1 antibody). The combination according to the present invention exhibits a high anti-tumor effect and is therefore useful for the treatment of cancer. |
| Author | TAKANO, Hirotsugu YOSHIDA, Takao SHOYAMA, Akiko |
| Author_xml | – fullname: YOSHIDA, Takao – fullname: SHOYAMA, Akiko – fullname: TAKANO, Hirotsugu |
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| Notes | Application Number: PH20191500002 |
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| PublicationDateYYYYMMDD | 2019-10-21 |
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| RelatedCompanies | ONO PHARMACEUTICAL CO., LTD |
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| Snippet | The present invention addresses the problem of discovering an effective cancer therapy method and providing a medicine. Provided is a medicine comprising a... |
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| Title | COMBINATION COMPRISING EP4 ANTAGONIST AND IMMUNE CHECKPOINT INHIBITOR |
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