DIHYDROPYRROLOPYRIDINE INHIBITORS OF ROR-GAMMA

Provided are novel compounds of Formula (I): pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of diseases and disorders mediated by RORy. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I) a...

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Main Authors CLAREMON, David, A, ZHUANG, Linghang, LOTESTA, Stephen, D, DILLARD, Lawrence, Wayne, ZHAO, Wei, FAN, Yi, SINGH, Suresh, B, ZHENG, Yajun, DONG, Chengguo, TICE, Colin, M, MARCUS, Andrew, JIA, Lanqi, YUAN, Jing
Format Patent
LanguageEnglish
Published 30.08.2017
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Abstract Provided are novel compounds of Formula (I): pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of diseases and disorders mediated by RORy. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I) and methods for their use in treating one or more inflammatory, metabolic, autoimmune and other diseases or disorders.
AbstractList Provided are novel compounds of Formula (I): pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of diseases and disorders mediated by RORy. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I) and methods for their use in treating one or more inflammatory, metabolic, autoimmune and other diseases or disorders.
Author SINGH, Suresh, B
DONG, Chengguo
DILLARD, Lawrence, Wayne
TICE, Colin, M
CLAREMON, David, A
ZHAO, Wei
FAN, Yi
JIA, Lanqi
MARCUS, Andrew
ZHUANG, Linghang
ZHENG, Yajun
LOTESTA, Stephen, D
YUAN, Jing
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– fullname: SINGH, Suresh, B
– fullname: ZHENG, Yajun
– fullname: DONG, Chengguo
– fullname: TICE, Colin, M
– fullname: MARCUS, Andrew
– fullname: JIA, Lanqi
– fullname: YUAN, Jing
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Snippet Provided are novel compounds of Formula (I): pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title DIHYDROPYRROLOPYRIDINE INHIBITORS OF ROR-GAMMA
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